Assisted Hatching
In a normal conception cycle, the human embryo hatches out of the zona
pellucida (the clear cover that surrounds the embryo) about seven days
after fertilization occurs. The embryo then implants on the uterine
surface and continues to grow. Many infertility specialists believe
that embryos may have difficulty hatching in older women and in some
women who have undergone IVF cycles without achieving pregnancy. Assisted
hatching is a procedure in which a small hole is made in the zona pellucida
to help the embryo hatch and implant. This procedure is performed under
a special microscope a few hours before the embryo transfer.